Dopamine D1 receptors are not critical for opiate reward but can mediate opiate memory retrieval in a state-dependent manner
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منابع مشابه
Dopamine D1 receptors are not critical for opiate reward but can mediate opiate memory retrieval in a state-dependent manner.
Although D1 receptor knockout mice demonstrate normal morphine place preferences, antagonism of basolateral amygdala (BLA) D1 receptors only during drug-naive rat conditioning has been reported to inhibit the expression of a morphine place preference. One possible explanation for this result is state-dependent learning. That is, the omission of the intra-BLA infusion cue during testing - which ...
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The use of very low concentrations of 1251-[D-Ala2,DLeu5]enkephalin, [3H]naloxone, and [3H]dihydromorphine under similar conditions enables the measurement of different opiate binding sites in a rat brain membrane preparation. In the absence of sodium ions, one such site binds enkephalins and their D-Ala2-substituted analogs with higher affinity than morphine and naloxone (enkephalin receptor),...
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ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2013
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2013.03.026